Tesamorelin (10mg)

Tesamorelin – Overview

What is Tesamorelin?

Tesamorelin is a synthetic analog of growth hormone-releasing hormone (GHRH) that stimulates the pituitary to produce and release growth hormone (GH). It is FDA-approved for reducing visceral adipose tissue (VAT) in HIV-associated lipodystrophy but is also used off-label for general fat loss, body composition improvement, and healthy aging. Tesamorelin offers precise GH stimulation with strong effects on metabolism and fat mobilization.

For Practitioners: Clinical Guidance

Mechanism of Action

Tesamorelin binds to GHRH receptors in the anterior pituitary, promoting natural GH secretion and downstream IGF-1 production. It increases lipolysis, improves insulin sensitivity, and reduces visceral fat accumulation. Its structure offers enhanced resistance to degradation and extended half-life compared to natural GHRH.

Benefits

• FDA-approved for reducing visceral abdominal fat
• Increases natural GH and IGF-1 production
• Supports improved body composition and fat metabolism
• May improve insulin sensitivity and lipid profiles
• Preserves physiologic GH pulsatility and avoids receptor desensitization

Dosing Protocol

• Typical Dose: 2 mg once daily
• Frequency: Daily (continuous use recommended for best results)
• Timing: Administer at night, ideally 90 minutes after eating
• Route: Subcutaneous injection
• Cycle Duration: Minimum 12–16 weeks; long-term use supported in clinical studies

Monitoring

• Monitor IGF-1 levels at baseline and regularly throughout therapy
• Track changes in visceral fat via waist circumference or imaging
• Optional: fasting glucose, lipids, and liver function if used long-term

For Patients: What You Should Know

What It Does

Tesamorelin helps your body naturally produce growth hormone, which helps burn deep belly fat, improve metabolism, and support better overall body composition.

Why You Might Use It

• Looking to reduce stubborn visceral (deep abdominal) fat
• Want to improve muscle tone and energy
• Managing age-related metabolic slowdown
• Seeking a natural way to support growth hormone production

How to Take It

• Inject under the skin once daily, usually at night
• Wait at least 90 minutes after your last meal before taking
• Take consistently as directed by your practitioner for best results

What to Expect

• Reduced belly fat and improved waistline over 8–12 weeks
• Better sleep, energy, and recovery with continued use
• Subtle improvements in strength and metabolism

Possible Side Effects

• Temporary injection site redness or itching
• Mild joint stiffness or bloating
• Rare: increased hunger or insulin sensitivity changes

Tesamorelin is a clinically proven peptide for reducing visceral fat and enhancing metabolic health—talk to your practitioner to find out how it can support your body composition and longevity goals.